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| Marassá,AM; Paula,MB; Gomes,AC; Consales,CA. |
| With a view toward investigating the feeding behavior of Culicidae mosquitoes from an area of epizootic yellow fever transmission in the municipalities of Garruchos and Santo Antônio das Missões, Rio Grande do Sul State, Brazil, specimens were collected by aspiration from September 2005 to April 2007. The engorged females were submitted to blood meal identification by enzyme-linked immunosorbent assay (ELISA). A total of 142 blood-engorged samples were examined for human or monkey blood through species-specific IgG. Additional tests for specificity utilizing isotypes IgG1 and IgG4 of human monoclonal antibodies showed that only anti-human IgG1 was effective in recognizing blood meals of human origin. The results indicated a significant difference (p =... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Culicidae; ELISA; Feeding habits; Isotypes; Yellow fever. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000400008 |
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| Dhalia,Rafael; Maciel Jr.,Milton; Cruz,Fábia S.P.; Viana,Isabelle F.T.; Palma,Mariana L.; August,Thomas; Marques Jr.,Ernesto T.A.. |
| Vaccination is the most practical and cost-effective strategy to prevent the majority of the flavivirus infection to which there is an available vaccine. However, vaccines based on attenuated virus can potentially promote collateral side effects and even rare fatal reactions. Given this scenario, the developent of alternative vaccination strategies such as DNA-based vaccines encoding specific flavivirus sequences are being considered. Endogenous cytoplasmic antigens, characteristically plasmid DNA-vaccine encoded, are mainly presented to the immune system through Major Histocompatibility Complex class I - MHC I molecules. The MHC I presentation via is mostly associated with a cellular cytotoxic response and often do not elicit a satisfactory humoral... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dengue; West Nile; Yellow fever; Lysosome-Associated Membrane Protein - LAMP; DNA vaccines. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000400005 |
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